Screening in Maternity to Ascertain Tuberculosis Status Study: Study Protocol

This study protocol was published to provide other researchers with access to the methodology and to provide background for a planned follow-up publication with the findings of the actual study. The study, conducted in Swaziland in 2016, evaluated the sensitivity and specificity of the current TB screening tool for pregnant and lactating women, both HIV-positive and HIV-negative.

The study also assessed an enhanced screening algorithm using different several laboratory and clinical procedures that have the potential to improve the sensitivity and specificity of the screening tool. These include a urine Lipoarabinomannan (LAM) test, Interferon-Gamma Release Assays (IGRA) blood tests, Tuberculin Skin Test (TST), chest radiography, and other medical histories.

Read the full journal article on BioMed Central.

Report Author(s): 
Edward Broughton, Samson Haumba, Marianne Calnan, Sandile Ginindsa, Rosanna Jeffries, Gugu Maphalala, Sikhathele Mazibuko, Munamato Mirara, Surbhi Modi, Pasipamire Munyaradzi, Peter Preko and Batsabile Simelane
BMC Infectious Diseases
ASSIST publication: 
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